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12 Signs of Pancreatic Cancer You Should Never Ignore

Posted on January 14, 2026 by Admin
Pancreatic cancer is often called a “silent” disease because its early symptoms can be subtle or mistaken for other conditions. Catching it early can make a significant difference, so being aware of warning signs is crucial. Here are 12 signs of pancreatic cancer you should never ignore:


1. Upper Abdominal Pain or Back Pain

  • Persistent discomfort in the upper abdomen or middle back.

  • Pain may worsen after eating or lying down.

2. Unexplained Weight Loss

  • Rapid or significant weight loss without changes in diet or exercise.

  • Often accompanied by loss of appetite.

3. Jaundice (Yellowing of Skin or Eyes)

  • Yellowing of the skin and the whites of the eyes.

  • Often accompanied by dark urine and pale stools.

4. Digestive Problems

  • Nausea, vomiting, bloating, or indigestion that doesn’t go away.

  • Trouble digesting fatty foods.

5. New-Onset Diabetes

  • Especially in adults over 50 with no family history.

  • Sudden high blood sugar levels may be a warning sign.

6. Pale, Greasy, or Floating Stools

  • Steatorrhea (fatty stools) caused by digestive enzyme blockage.

  • Stools may appear light-colored, bulky, or foul-smelling.

7. Loss of Appetite

  • Feeling full quickly or lack of interest in eating.

  • May contribute to weight loss.

8. Itchy Skin

  • Caused by bile salt buildup from blocked bile ducts.

  • Can appear before visible jaundice.

9. Blood Clots

  • Swelling, pain, or redness in the legs (deep vein thrombosis).

  • Blood clots may occur in unusual locations without clear reason.

10. Fatigue

  • Persistent tiredness that doesn’t improve with rest.

  • Often due to cancer-related metabolic changes.

11. Indigestion or Heartburn

  • Ongoing digestive discomfort or reflux that doesn’t respond to medication.

12. Unexplained Fever or Night Sweats

  • Can indicate an immune response to cancer or related inflammation.


⚠️ Important Notes

  • These symptoms can be caused by other, less serious conditions.

  • Persistent or worsening symptoms should never be ignored.

  • Early detection is key: if you notice one or more of these warning signs, see a doctor—ideally a gastroenterologist—for evaluation.


If you want, I can also create a quick checklist you can use to track these warning signs for yourself or a loved one, which can be handy before visiting a doctor. Do you want me to make that?

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